Michael Whitlock
Week
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Topics
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| 1
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Review
of allele frequencies, Hardy-Weinberg equilibrium, and linkage equilibrium;
Hardy-Weinberg equilibrium for multiple alleles and loci
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| 2
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Drift
: Identity by descent, diffusion, the coalescent
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| 3
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Effective
population size
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| 4
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Mutation:
Types of mutations, mutation and drift, neutral theory
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| 5
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Selection:
Defining and measuring fitness, single locus models
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| 6
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Mutation
selection balance, frequency dependent selection, gametic selection
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| 7
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Selection
and drift, selection on two or more loci, estimating selection
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| 8
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Inbreeding:
Calculation of inbreeding coefficients, mating system evolution
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| 9
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Population
Subdivision and Migration: Wahlund effect, F statistics, genetic
distance
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| 10
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Models
of population structure, migration and drift, interdemic selection
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| 11
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Quantitative
Genetics: Heritability, estimating heritability, response to selection
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| 12
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Genetic
basis of quantitative traits, sources of variance, norms of reaction
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| 13
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Maintenance
of quantitative variation, response to multivariate selection
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